Arana Therapeutics
Arana Therapeutics
 

Intellectual Property

Arana’s patent position reflects the company’s focus on ensuring market exclusivity for lead therapeutic products in development. The company continues to pursue an aggressive policy of patenting discoveries and maximising patent coverage, with continual assessment of our own inventions and those of others in related areas that may impact on commercialisation of Arana’s products.

Arana’s current portfolio consists of 60 patent families with protection for its inventions being sought in major competitive markets including the U.S., Europe, Japan, Canada, Australia, China and India.

Arana scientists are aware of the importance of patents to the company and pay careful attention to the possibility of filing further applications as projects progress.

In the past 12 months, Arana has been granted some key patent rights for the protection of the following:

  • PMX53 compound in Europe
  • Use of PMX53 in the treatment of ulcerative colitis in
    the U.S.
  • ART101 in Australia
Patent families – income generation
Several of Arana’s patent families form the basis of the company’s income. Some of the patents listed below relate to anti-TNF (tumour necrosis factor), antibody humanisation by Superhumanisation™ and affinity maturation by EvoGene™ technologies.

Arana Therapeutics
 
PCT Number PCT Title Filing Date
PCT/AU90/00337 Tumour necrosis factor binding ligands 7 September 1990
PCT/AU99/00341 Continuous in-vitro evolution 7 May 1999
PCT/AU03/01455
Mutagenesis methods using ribavirin and/or
RNA replicases
3 November 2003
PCT/US02/022011 Super humanized antibodies 12 July 2002

Patent families – product development
In the course of developing therapeutic products, Arana aims to prosecute existing patents and file new applications. Some key patents relating to our lead projects including ART621, ART010, ART150, ART104 and PMX53 are listed below.

PCT Number PCT Title Filing Date
PCT/AU2006/001940 Anti-inflammatory dAb 20 December 2006
PCT/AU2007/000085 Domain antibody construct 1 February 2007
PCT/GB2005/001805


Monoclonal antibody SC104 and derivative thereof specifically binding to a sialyltetraosyl carbohydrate as a potential anti-tumour therapeutic agent 11 May 2005

 
PCT/AU05/001877 Osteoprotegerin variant proteins 13 December 2005
PCT/US00/19589 Anti-tumour antibodies, proteins and uses thereof 18 July 2000
PCT/AU98/00490
 
Cyclic agonists and antagonists of C5a receptors and G-protein-coupled receptors 25 June 1998